Review 2022 · 5 atıf

Sepsis: Immunopathology, Immunotherapies, and Future Perspectives

Özet

Sepsis is a syndrome that includes physiological, pathological, and biochemical abnormalities resulting from the host immune response to infection. Despite the improved treatment modalities in recent years, the incidence and mortality of sepsis are still increasing. Sepsis immunopathology is increasingly attracting the attention of researchers. The successes experienced with immunotherapeutics in the treatment of cancer and coronavirus disease 2019, which are diseases with similar pathophysiological features and common immune defects with sepsis, have given rise to the hope that similar successes can be achieved in the treatment of sepsis. In this review, future perspectives on the immunopathology of sepsis and immunotherapeutics are presented to improve the current understanding of the disease.

Anahtar Kelimeler

Sepsis immunotherapy immunopathology TUMOR-NECROSIS-FACTOR SEPTIC SHOCK DOUBLE-BLIND INDUCED IMMUNOSUPPRESSION MONOCLONAL-ANTIBODY ANTIOXIDANT ENZYMES IMMUNE DYSFUNCTION IMPROVES SURVIVAL CECAL LIGATION RAT MODEL

WoS Kategorileri

Medicine, General & Internal

Sürdürülebilir Kalkınma Amaçları

Sağlık ve Kaliteli Yaşam

Künye

Dergi: EURASIAN JOURNAL OF MEDICINE
Yıl: 2022
Cilt: 54
Sayfa: S127-S132
eISSN: 1308-8742
DOI: 10.5152/eurasianjmed.2022.22314
WoS UID: WOS:000926902700019

Yayını aç (DOI)