CUMYL-4CN-BINACA exposure is associated with oxidative stress, ER stress-related responses, apoptosis, and altered KIM-1, NGAL, and nephrin expression in rat kidney.

Esra Aktaş Şenocak, Özkan Aksakal, Cihan Gür, İlyas Bozkurt, İsmail Bolat, Mesut Bünyami Halıcı

Osajin attenuates diazinon-induced pulmonary toxicity in rats

İlyas Bozkurt, Esra Aktaş Şenocak, Tuba Karaarslan, Ömercan Alat, Cihan Gür, Volkan Ay, Mustafa İleritürk, İsmail Can, Mesut Bünyami Halıcı

• WoS Q1
• Scopus Q3

Chronic Toxicity of the Synthetic Pyrethroid Tau Fluvalinate to Aquatic Invertebrates: Life History, Oxidative Stress, and Molecular Responses of Daphnia magna

Hatice Dane, Özkan Aksakal, Cihan Gür, Ömercan Alat

• WoS Q2
• Scopus Q2
• WoS 1 atıf
• Scopus 1 atıf
• PlumX

Protective effects of morin on colistin-induced neurotoxicity in rats via modulation of oxidative, inflammatory, apoptotic, and autophagic alterations

HİLAL GÖREN, CÜNEYT ÇAĞLAYAN, RAMAZAN ÇINAR, Sefa Küçükler, Nurhan Akaras, Cihan Gür, Fatih Mehmet KANDEMİR

• WoS Q1
• Scopus Q3
• WoS 1 atıf

The histopathological and molecular protective effects of sinapic acid against lead acetate–induced cardiac damage via NRF2/HO-1 and ER stress–related pathways

Özge Kandemir, Fatih Mehmet KANDEMİR, Sefa Küçükler, Nurhan Akaras, Cihan Gür, Mustafa İleritürk, Hasan Şimşek, Murat Gül

• WoS Q2
• Scopus Q1

Developmental and systemic toxicity of the triazole fungicide tetraconazole in zebrafish: Integrated evidence from ER stress, apoptosis, and metabolomic disruption

Feyza İcoglu Aksakal, Turgay Şişman, Cihan Gür, Onur Şenol, Özkan Aksakal

• WoS Q1
• Scopus Q1
• WoS 2 atıf
• Scopus 2 atıf
• PlumX

Effects of dietary supplementation of methylsulfonylmethane on performance, egg quality, serum biochemical parameters, and malondialdehyde levels in feed-restricted laying hens

Emre Yılmaz, Cihan Gür, Mehmet Gül

• WoS Q2
• Scopus Q1

Immune activation and endoplasmic reticulum stress-mediated apoptosis in dogs naturally infected with Ehrlichia canis

Kerim Emre Yanar, Cihan Gür, Rıdvan KİRMAN, Mustafa Sinan Aktaş, Sümeyye Baysal

• WoS Q2
• Scopus Q2

Multi-level assessment of chronic toxicity of the insect growth regulator lufenuron in the non-target aquatic organism Daphnia magna

Hatice Dane, Özkan Aksakal, Turgay Şişman, Cihan Gür, Ömercan Alat

• WoS Q1
• Scopus Q1
• PlumX

Integrated molecular and metabolomic assessment of copper hydroxide nanopesticide toxicity in zebrafish

Feyza Icoglu Aksakal, Cihan Gür, Turgay Şişman, Semih Özli, Onur Şenol, Özkan Aksakal

• WoS Q2
• Scopus Q2
• PlumX

Sinapic acid attenuates vancomycin-induced hepatotoxicity in rats via modulation of ER stress (CHOP, IRE1, ATF-6, PERK), apoptotic pathways (caspase-3, Bax/Bcl-2, Apaf-1, cytochrome-c), and antioxidant defenses

Cihan Gür, Mustafa İleritürk, Nurhan Akaras, Fatih Mehmet Kandemir

• WoS Q1
• Scopus Q3
• WoS 4 atıf

Ameliorative Effects of Royal Jelly Against Ibuprofen-Induced Hepatic Toxicity: Molecular Regulation via Oxidative Stress, Cytokine Signaling, Cell Death Mechanisms, and Endoplasmic Reticulum Stress

CÜNEYT ÇAĞLAYAN, HİLAL GÖREN, Cihan Gür, Sefa Küçükler, RAMAZAN ÇINAR, Nurhan Akaras, Fatih Mehmet KANDEMİR, AYŞE AYDINOĞLU

• WoS Q2
• Scopus Q2

Impact of chronic cold stress on metabolism, colostrum quality, and lamb performance in locally adapted ewes

Ayşe Uysal, Emre Yılmaz, Cihan Gür, Soner Uysal, Doğan Türkyılmaz, Ülkü Dağdelen Türkyılmaz

• WoS Q2
• Scopus Q2

Protocatechuic acid mitigates diazinon-induced lung injury in rats through modulation of oxidative stress, inflammatory, Keap-1/Nrf-2/HO-1 and ER stress-mediated apoptotic pathways

Tuba Karaarslan, Ömercan Alat, Ismail Can, Esra Aktaş Şenocak, Cihan Gür, Ilyas Bozkurt, Mohammad Alhilal, Mesut Bünyami Halıcı

• WoS Q2
• Scopus Q2
• WoS 2 atıf

Investigating the Effects of Apilarnil on Vincristine-Induced Testicular Toxicity in Rats

Metin Takkac, Serkan Ali Akarsu, Gamze Uçak, Sefa Küçükler, Cihan Gür, Nurhan Akaras, Mustafa İLERİTÜRK, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q2
• WoS 2 atıf

The synthetic cannabinoid CUMYL-4CN-BINACA induces hepatic injury in rats via oxidative stress, NF-κB activation, Nrf2 suppression, EDEM-1, ER stress-mediated apoptotic pathways

Tuba Karaarslan, Özkan Aksakal, Ömercan Alat, Mesut Bünyami Halıcı, Cihan Gür

• WoS Q2
• Scopus Q1
• WoS 5 atıf
• Scopus 7 atıf
• PlumX

Investigation of protective effects of rutin\cyclodextrin inclusion complex against testicular damage caused by diisononyl phthalate in rats

Ramazan Bozali, Serkan Ali Akarsu, Cihan Gür, Ömer AYDIN, Nurhan Akaras, Mustafa İleritürk, Serhat Sunar, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q2
• WoS 1 atıf

Carvacrol mitigates Mercury chloride induced neurotoxicity by regulation of NRF-2/HO-1/NF-κB expression

Nurhan Akaras, Hasan Şimşek, Mustafa İleritürk, Sefa Küçükler, Cihan Gür, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q2
• WoS 7 atıf

Zingerone ameliorates sodium arsenite-induced cardiotoxicity in rats by suppressing oxidative stress and inflammation via Nrf2 /GCLM\GCLC signaling pathways

Özge Kandemir, Fatih Mehmet Kandemir, Nurhan Akaras, Sefa Küçükler, Cihan Gür, Mustafa İLERİTÜRK, Hasan Şimşek, Murat Gül

• WoS Q2
• Scopus Q2
• WoS 5 atıf

Hesperidin ameliorates vancomycin-induced kidney injury via multipathway modulation: Nrf-2/HO-1, Caspase-3/Bax/Bcl-2, ATF-4, KIM-1 and improved renal tissue function

Selman Gencer, Hasan Şimşek, Nurhan Akaras, Mustafa İleritürk, Cihan Gür, Sefa Küçükler, Nazım Abdülkadir Kankılıç, Fatih Mehmet Kandemir

• WoS Q1
• Scopus Q1
• WoS 7 atıf

Protective Effects of Berberine on Bortezomib-Induced Hepatorenal Toxicity in Sprague Dawley Rats: Biochemical, Molecular and Histological Evaluation

Ozge Kandemir, Cihan Gür, Selim Çomaklı, Sefa Küçükler, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q2
• WoS 4 atıf

Synthetic cannabinoid CUMYL-4CN-BINACA induces oxidative stress, ER stress, and apoptosis in brain and testicular tissues of male albino rats

Erdem Eren Demir, Cihan Gür, Turgay Şişman, Ayse Lafzi, Özkan Aksakal

• WoS Q2
• Scopus Q1
• WoS 8 atıf
• Scopus 10 atıf
• PlumX

Nephroprotective effects of hesperidin on ifosfamide-induced acute nephrotoxicity in rats: Role of NF-κB/TNF-α/ IL-1β p53/caspase-3/Bax/ Bcl-2, and ATF6/IRE1/PERK/GRP78 signaling pathways

Özge Kandemir, Nurhan Akaras, Hasan Şimşek, Cihan Gür, Mustafa İLERİTÜRK, Sefa Küçükler, CÜNEYT ÇAĞLAYAN, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q2
• WoS 19 atıf

Potent Ameliorative Effects of Rosmarinic Acid on Tramadol-Induced Neurotoxicity in the Brain and Hippocampus; by Suppressing Oxidative stress, Apoptosis, ER stress, and Regulating Cognitive Functions

Onur Karaca, Hasan Şimşek, Nurhan Akaras, Cihan Gür, Mustafa İleritürk, Özge Kandemir, Sefa Küçükler, Şeyda Öte Karaca, Fatih Mehmet Kandemir

• WoS Q1
• Scopus Q1
• WoS 11 atıf

Carvacrol Coadministration Ameliorates Lambda-Cyhalothrin-Induced Peripheral Neuropathy in Rats: Behavioral and Molecular Evidence

Özge Kandemir, Mustafa İleritürk, Cihan Gür, Nurhan Akaras, Hasan Şimşek, Selçuk Yılmaz, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q2
• WoS 4 atıf

Morin Attenuates Diclofenac-Induced Hepatocellular Death Injury via Nrf2/Ho-1/NQO1, Beclin-1/LC3A/LC3B and p53/Bax/Caspase Signalling Pathways

Nurhan Akaras, Hasan Şimşek, Cihan Gür, Sefa Küçükler, Mustafa İleritürk, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q2
• WoS 8 atıf

Protective Effects of Chrysin Against Diclofenac-Induced Nephrotoxicity in Rats via Attenuation of Oxidative Stress, Apoptosis and Endoplasmic Reticulum Stress

CÜNEYT ÇAĞLAYAN, İzzettin Ekinci, Cihan Gür, Adnan Ayna, İbrahim Bayav, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q2
• WoS 28 atıf

The Protective Effects of Chrysin on Acrylamide-Induced Hepatotoxicity: Insights Into Oxidative Stress, Inflammation, Apoptosis, Autophagy, and Histological Evaluation in Rats

Selman Gencer, Nurhan Akaras, Hasan Şimşek, Cihan Gür, Mustafa İleritürk, Sefa Küçükler, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q2
• WoS 11 atıf

Ameliorative effect of morin on diclofenac-induced testicular toxicity in rats: An investigation into different signal pathways

Hasan Şimşek, Nurhan Akaras, Cihan Gür, Sefa Küçükler, Mustafa İLERİTÜRK, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q2
• WoS 13 atıf

Hepatoprotective Effects of Royal Jelly Against Vincristine-Induced Hepatotoxicity in Rats: A Biochemical and Molecular Study

Rahime Erzincan, CÜNEYT ÇAĞLAYAN, Fatih Mehmet Kandemir, Ebubekir İzol, Cihan Gür, Mustafa İLERİTÜRK

• WoS Q1
• Scopus Q1
• WoS 13 atıf

Therapeutic potential of rosmarinic acid in tramadol-induced hepatorenal toxicity: Modulation of oxidative stress, inflammation, RAGE/NLRP3, ER stress, apoptosis, and tissue functions parameters

Onur Karaca, Nurhan Akaras, Hasan Şimşek, Cihan Gür, Mustafa İLERİTÜRK, Sefa Küçükler, Selman Gencer, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q1
• WoS 14 atıf

Cardiotoxicity caused by acrylamide in rats can be alleviated as a result of suppression of oxidative stress, endoplasmic reticulum stress, inflammation, and apoptosis by morin treatment

Fatma Cakmak, Sefa Küçükler, Cihan Gür, Mustafa İLERİTÜRK, Murat Gul, Behcet Varisli

• WoS Q2
• Scopus Q2
• WoS 3 atıf

Chronic toxicity of tetraconazole and penconazole to Daphnia magna: Insights of growth, reproduction and gene expression changes

Özkan Aksakal, Hatice Dane, Cihan Gür, Turgay Şişman

• WoS Q1
• Scopus Q1
• Scopus 9 atıf
• PlumX

Docetaxel-induced liver and kidney toxicity in rats can be alleviated by suppressing oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis and autophagy signaling pathways after Silymarin treatment

Ozge Kandemir, Sefa Küçükler, Selim ÇOMAKLI, Cihan Gür, Mustafa İleritürk

• WoS Q2
• Scopus Q1
• WoS 11 atıf

Protective Effects of Carvacrol on Mercuric Chloride-Induced Lung Toxicity Through Modulating Oxidative Stress, Apoptosis, Inflammation, and Autophagy

Berna Eriten, Sefa Küçükler, Cihan Gür, Adnan Ayna, Halit Diril, CÜNEYT ÇAĞLAYAN

• WoS Q2
• Scopus Q1

β-carotene protects against α-amanitin nephrotoxicity via modulation of oxidative, autophagic, nitric oxide signaling, and polyol pathways in rat kidneys

Arzu Gezer, HİLAL ÜSTÜNDAĞ, Ebru Karadağ Sarı, Gürsel Bedir, Cihan Gür, Ali Sefa Mendil, Lale Duysak

• WoS Q2
• Scopus Q1
• WoS 4 atıf
• Scopus 6 atıf
• PlumX

Ameliorative effects of sinapic acid against vancomycin-induced testicular oxidative damage, apoptosis, inflammation, testicular histopathologic disorders and decreased epididymal sperm quality

Serkan Ali Akarsu, Mustafa İleritürk, Sefa Küçükler, Nurhan Akaras, Cihan Gür, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q2
• WoS 18 atıf

Protective Effects of Syringic Acid Against Oxidative Damage, Apoptosis, Autophagy, Inflammation, Testicular Histopathologic Disorders, and Impaired Sperm Quality in the Testicular Tissue of Rats Induced by Mercuric Chloride

Serkan Ali Akarsu, Cihan Gür, Sefa Küçükler, Nurhan Akaras, Mustafa İleritürk, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q1

Carvacrol Reduces Mercuric Chloride-Induced Testicular Toxicity by Regulating Oxidative Stress, Inflammation, Apoptosis, Autophagy, and Histopathological Changes

Hasan Simsek, Cihan Gür, Sefa Küçükler, Mustafa İleritürk, Nurhan Akaras, Mehmet Oz, FATİH MEHMET KANDEMİR

• WoS Q2
• Scopus Q1
• WoS 31 atıf

The ameliorative effect of carvacrol on sodium arsenite-induced hepatotoxicity in rats: Possible role of Nrf2/HO-1, RAGE/NLRP3, Bax/Bcl-2/Caspase-3, and Beclin-1 pathways

Selman Gencer, Cihan Gür, Mustafa İleritürk, Sefa Küçükler, Nurhan Akaras, Hasan Şimşek, Fatih M. Kandemir

• WoS Q2
• Scopus Q2
• WoS 39 atıf

Hepatoprotective effects of zingerone on sodium arsenite-induced hepatotoxicity in rats: Modulating the levels of caspase-3/Bax/Bcl-2, NLRP3/NF-κB/TNF-α and ATF6/IRE1/PERK/GRP78 signaling pathways

Berna Eriten, CÜNEYT ÇAĞLAYAN, Cihan Gür, Sefa Küçükler, Halit Diril

• WoS Q3
• Scopus Q2
• WoS 13 atıf

The ameliorative effects of chrysin on bortezomib-induced nephrotoxicity in rats: Reduces oxidative stress, endoplasmic reticulum stress, inflammation damage, apoptotic and autophagic death

Nazım Abdülkadir Kankılıç, Hasan Şimşek, Nurhan Akaras, Cihan Gür, Sefa Küçükler, Mustafa İleritürk, Selman Gencer, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q1
• WoS 37 atıf

Sinapic acid protects against lead acetate-induced lung toxicity by reducing oxidative stress, apoptosis, inflammation, and endoplasmic reticulum stress damage

NURHAN AKARAS, Sefa Küçükler, Cihan Gür, Mustafa İleritürk, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q1
• WoS 20 atıf

Naringin protects against paclitaxel-induced toxicity in rat testicular tissues by regulating genes in pro-inflammatory cytokines, oxidative stress, apoptosis, and JNK/MAPK signaling pathways

Nazim Abduelkadir Kankilic, Sefa Küçükler, Cihan Gür, Serkan Ali Akarsu, Nurhan Akaras, Hasan Simsek, Mustafa İleritürk, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q2
• WoS 40 atıf

Effects of zingerone on rat induced testicular toxicity by sodium arsenite via oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, and autophagy pathways

Sibel Çiǧdem Tuncer, Cihan Gür, Sefa Küçükler, Serkan Ali Akarsu, Fatih Mehmet Kandemir

• WoS Q2
• Scopus Q2
• WoS 19 atıf

Zingerone attenuates sciatic nerve damage caused by sodium arsenite by inhibiting NF-κB, Caspase-3, and ATF-6/CHOP pathways and activating the Akt-2/FOXO1 pathway

Selcuk Yilmaz, Cihan Gür, Sefa Kucukler, Nurhan AKARAS, FATİH MEHMET KANDEMİR

• WoS Q2
• Scopus Q2
• WoS 18 atıf

Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology

Nurhan Akaras, Cihan Gür, CÜNEYT ÇAĞLAYAN, FATİH MEHMET KANDEMİR

• WoS Q2
• Scopus Q2
• WoS 32 atıf

Protective effects of naringin on colistin-induced damage in rat testicular tissue: Modulating the levels of Nrf-2/HO-1, AKT-2/FOXO1A, Bax/Bcl2/Caspase-3, and Beclin-1/LC3A/LC3B signaling pathways

Nazım Abdülkadir Kankılıç, Hasan Şimşek, Nurhan Akaras, Cihan Gür, Mustafa İleritürk, Sefa Küçükler, Serkan Ali Akarsu, Fatih M. Kandemir

• WoS Q2
• Scopus Q2
• WoS 30 atıf

Insulin-like growth factor-1 expression levels in pro-inflammatory response in calves with neonatal systemic inflammatory response syndrome

Kerim Emre Yanar, Cihan Gür, Şükrü DEĞİRMENÇAY, Ömer Aydın, Mustafa Sinan Aktaş, Sümeyye Baysal

• WoS Q2
• Scopus Q1
• WoS 6 atıf

PROTECTIVE EFFECT OF HESPERIDIN ON OXIDATIVE STRESS, INFLAMMATION AND APOPTOSIS IN ABAMECTIN-INDUCED GASTRIC TOXICITY

SİBEL ÇİĞDEM TUNCER, Cihan Gür, HASAN ŞİMŞEK, FATİH MEHMET KANDEMİR

SIMULTANEOUS ADMINISTRATION OF SINAPIC ACID AMELIORATES VANCOMYCIN-INDUCED GASTRIC DAMAGE IN RATS: BIOCHEMICAL AND MOLECULAR EVIDENCE

Cihan Gür, SERPİL AYGÖRMEZ

PROTECTIVE ROLE OF BORAGO OFFICINALIS ON LEAD ACETATE-INDUCED LUNG TOXICITY IN RATS: INVOLVEMENT OF Nrf2/Keap1/HO-1 and NF-κB/TNF-α SIGNALING PATHWAYS ASSESSED BY WESTERN BLOT ANALYSIS

Tuba Karaarslan, Cihan Gür

RAT MODELİNDE MALATHİON VE RUTİN UYGULAMALARININ KARACİĞER VE BÖBREK DOKULARI ÜZERİNDEKİ ETKİLERİNİN NF-B, ATF-6/CHOP VE APAF-1/KASPAZ-3 YOLAKLARI KULLANILARAK KARŞILAŞTIRILMASI

Cihan Gür, FATİH MEHMET KANDEMİR

CARVACROL REDUCES ABNORMAL AND DEAD SPERM COUNTS BY ATTENUATING SODIUM ARSENITE-INDUCED OXIDATIVE STRESS, INFLAMMATION, APOPTOSIS AND AUTOPHAGY IN TESTICULAR TISSUES OF RATS

Cihan Gür, Serkan Ali Akarsu, FATİH MEHMET KANDEMİR

Kuersetin Ratlarda Sipermetrin Kaynaklı Dalak Toksisitesini Oksidatif Stres, Endoplazmik Retikulum Stresi ve Apoptozu Baskılayarak Hafifletir

Cihan Gür

Chrysin Alleviates Gastric Toxicity Caused by Lead Acetate by Showing Anti-oxidant and Anti-inflammatory Effects

Cihan Gür

Biochemical Evaluation of Anti-Inflamatuar, Anti-Apoptotic And Anti-Otophagic Properties Of Silimarine And Naringin on Methodrexate-Induced Nephrotoxicity in Rats.

FATİH MEHMET KANDEMİR, Sefa Küçükler, CÜNEYT ÇAĞLAYAN, Cihan Gür, annour BATIL, İlhami Gülçin

Ratlarda, Metotreksat ile İndüklenen Nefrotoksisite Üzerine, Silimarin ve Naringinin Anti-Oksidan, Anti-Enflamatuar, Anti-Apoptotik ve Anti-Otofajik Özelliklerinin Biyokimyasal Olarak Değerlendirilmesi

FATİH MEHMET KANDEMİR, Sefa Küçükler, CÜNEYT ÇAĞLAYAN, Cihan Gür, ANNOUR ADOUM BATIL, İlhami Gülçin

General Evaluation of Cytokine Response in Sepsis

Seçkin Özkanlar, Cihan Gür

The Effects of Bromelain Supplementation into the Broiler Rasion on Liver Tissues

Seçkin Özkanlar, Güler Yenice, Cihan Gür, Semin Gedikli