Review 2025 · 4 citations

Chronic postsurgical pain after cardiac surgery: A narrative review

Dost, Burhan, Karapinar, Yunus Emre, Karakaya, Deniz, Demir, Zeliha Asli, Baris, Sibel, Koksal, Ersin, Aydin, Muhammed E., Ciftci, Bahadir, Tulgar, Serkan

Abstract

Chronic postsurgical pain (CPSP) is a prevalent and debilitating sequela of cardiac surgery, exerting a profound impact on patients' quality of life, functional recovery, and healthcare systems. Its pathophysiology includes complex mechanisms, including peripheral and central sensitization, neuroplastic alterations, and inflammatory pathways, influenced by demographic, psychological, and perioperative factors. Inadequate management of acute pain is a critical contributor to its development. This review examines the etiology of CPSP, presents key risk factors, and critically evaluates pharmacological and nonpharmacological interventions. Particular attention is devoted to the role of regional anesthesia techniques and emerging preventive and therapeutic strategies, highlighting the necessity of multidisciplinary, evidence-informed approaches to address this persistent clinical challenge.

Keywords

Cardiac surgery chronic postsurgical pain regional anesthesia SPINAE PLANE BLOCK PERSISTENT POSTOPERATIVE PAIN THORACIC EPIDURAL-ANESTHESIA RISK-FACTOR IDENTIFICATION PREVALENCE MANAGEMENT PREVENTION CHILDREN PATHOPHYSIOLOGY REMIFENTANIL

WoS Categories

Anesthesiology

Sustainable Development Goals

Good Health and Well-being

Citation

Journal: SAUDI JOURNAL OF ANAESTHESIA
Year: 2025
Volume: 19
Issue: 2
Pages: 181-189
ISSN: 1658-354X
eISSN: 0975-3125
DOI: 10.4103/sja.sja_829_24
WoS UID: WOS:001451036700008

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