Article 2024 · 1 citations

Antidiabetic Effect of Fig Seed Oil in Rats with Diabetes Induced by Streptozotocin

Mert, Handan, Mert, Nihan, Cibuk, Salih, Yildirim, Serkan, Mert, Nihat

Abstract

The anti -diabetic effect of Ficus carica (Fig) seed oil was investigated. 4 groups with 6 rats in each group were used in the experiment as control, diabetes (45 mg/kg streptozotocin), fig seed oil (FSO) (6 mL/ kg/day/rat by gavage) and diabetes+FSO groups. Glucose, urea, creatinine, ALT, AST, GSH, AOPP and MDA analyses were done. Pancreatic tissues were examined histopathologically. When fig seed oil was given to the diabetic group, the blood glucose level decreased. In the diabetes+FSO group, serum urea, creatinine, AOPP, MDA levels and ALT and AST activities decreased statistically significantly compared to the diabetes group, while GSH levels increased significantly, histopathological, immunohistochemical, and immunofluorescent improvements were observed. It has been shown for the first time that FSO has positive effects on blood glucose level and pancreatic health. It can be said that the protective effect of fig seed oil on tissues may be due to its antioxidant activity.

Keywords

fig seed oil diabetes rat histopathology glucose CARICA LEAF EXTRACT FICUS-CARICA OXIDATIVE STRESS IN-VITRO PROTEIN ANTIOXIDANT ENZYMES FRUITS LATEX

WoS Categories

Chemistry, Applied Food Science & Technology

Sustainable Development Goals

Good Health and Well-being

Citation

Journal: JOURNAL OF OLEO SCIENCE
Year: 2024
Volume: 73
Issue: 5
Pages: 717-727
ISSN: 1345-8957
eISSN: 1347-3352
DOI: 10.5650/jos.ess23255
WoS UID: WOS:001222840400007

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