Article 2023 · 1 citations

Clinical characteristics and outcomes of nosocomial COVID-19 in Turkey: A retrospective multicenter study

Yildirim, Suleyman, Yilmaz, Celalettin, Polat, Gulru, Baris, Serap, Basyigit, Ilknur, Kaya, Ilknur, Anar, Ceyda, Bozkurt, Mihriban, Baykal, Huesnue, Dirol, Hulya, Ozbey, Gamzenur, Ozsari, Emine, Cireli, Emel, Ciirak, Ali, Tatar, Dursun, Gayaf, Mine, Karaoglanoglu, Selen, Aydin, Yener, Eroglu, Atilla, Olcar, Yildiz, Yildirim, Berna, Gursoy, Bengul, Yilmaz, Deniz, Niksarlioglu, Elif, Eren, Ramazan, Erdem, Aysegul, Tor, Muge Meltem, Fakili, Fusun, Colak, Mustafa, Ercelik, Merve, Tabaru, Ali, Ediboglu, Ozlem

Abstract

Objective: To identify the clinical characteristics and outcomes of hospital-acquired SARS-CoV-2 infection during the vaccination period nationwide in Turkey. Methods: COVID-19 patients followed in the pandemic services across Turkey between January 1, 2021, and March 31, 2022 were investigated retrospectively. Nosocomial COVID-19 was defined as a patient neither diagnosed with COVID-19 nor suspected COVID-19 at the hospital admission and was confirmed COVID-19 >= 5 days after hospital admission. The primary outcome of this study was in-hospital mortality; demographic features and vaccination status was compared between survivors and non survivors. Results: During the study period, 15 573 COVID-19 patients were followed in 18 centers and 543 (3.5%) patients were nosocomial COVID-19. Most patients with nosocomial COVID-19 (80.4%) were transferred from medical wards. 162 (29.8%) of the patients with nosocomial COVID-19 admitted to the intensive care unit due to disease severity and 138 (25.4%) of the patients died during hospital stay. Advanced age (>= 65 years) and number of comorbid diseases (>= 2) was found to be associated with mortality in nosocomial COVID-19 (OR 1.74, 95% CI 1.11-2.74 and OR 1.60, 95% CI 1.02-2.56, respectively). Vaccination was associated with survival in nosocomial COVID-19 (OR 0.25, 95% CI0.16-0.38). Conclusions: Patients with nosocomial COVID-19 had increased admission to intensive care units and higher mortality rate. Vaccination can decrease the in-hospital mortality rate.

Keywords

COVID-19 Nosocomial infection Vaccination Intensive care unit INFECTION RISK MORTALITY CANCER

WoS Categories

Public, Environmental & Occupational Health Tropical Medicine

Sustainable Development Goals

Good Health and Well-being

Citation

Journal: ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE
Year: 2023
Volume: 16
Issue: 8
Pages: 347-353
ISSN: 1995-7645
eISSN: 2352-4146
DOI: 10.4103/1995-7645.383912
WoS UID: WOS:001142330900005

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