Review 2023 · 0 citations

The fine line between occupational exposure and addiction to propofol

Palabiyik-Yucelik, Saziye Sezin, Yoladi, Fatma Betul, Yegenoglu, Selen, Baydar, Terken

Abstract

Addiction is considered as an occupational hazard, especially in anesthesia units in hospitals. Professionals in anesthesiol-ogy clinics have easy access to a wide range of potent psychoactive drugs, causing them to have a higher risk of drug abuse compared to other healthcare personnel. Recent studies and case reports have shown that abuse of anesthetic drugs used in these units has become a problem among health professionals, and awareness of the problem has increased. Propofol is widely used in anesthesia as a sedative-hypnotic prescription drug and in the literature, propofol abuse is mostly referred to in connection with medical and paramedical personnel. In this manuscript, we reviewed the pharmaco-kinetics, -dynam-ics effect of propofol, discussed toxicological outcomes of propofol abuse and possible institutional measures to be taken against addiction.

Keywords

Propofol addiction abuse anesthetics 2ND-HAND EXPOSURE SUBSTANCE-ABUSE DEPENDENCE FENTANYL LETHAL SENSITIZATION ANESTHESIA DEATH

WoS Categories

Pharmacology & Pharmacy

Citation

Journal: ISTANBUL JOURNAL OF PHARMACY
Year: 2023
Volume: 53
Issue: 1
Pages: 95-102
eISSN: 2587-2087
DOI: 10.26650/IstanbulJPharm.2023.1134975
WoS UID: WOS:000995958300014

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