A new marker for the prediction of contrast induced-acute kidney injury following primary percutaneous coronary intervention: logarithm of haemoglobin-albumin product
Ozveren, Olcay, Tanalp, Ali Cevat, Tanboga, Ibrahim Halil, Karagoz, Ali, Saygi, Mehmet, Birdal, Oguzhan, Turkyilmaz, Erdem, Durmus, Erdal, Oduncu, Vecih
BackgroundContrast-induced acute kidney injury (CI-AKI) is a disorder that adversely affects the prognosis of STEMI. The study aimed to assess the predictive value of a new marker, logarithm of haemoglobin and albumin product (LHAP) on the risk of CI-AKI development after primary percutaneous coronary intervention (p-pci).MethodWe retrospectively enrolled 3057 patients with ST-elevation acute myocardial infarction who were treated with p-PCI. The primary outcome was CI-AKI, defined as >25% or >0.5 mg/dl increase of baseline creatinine values during post-procedural 48 h.ResultsFirst, a baseline model was produced to determine the predictors of CI-AKI, then haemoglobin, albumin and LHAP were included in the base model and the performances of all models were compared. The predictive accuracy (Likelihood ratio chi(2) and R-2) and discrimination (ROC-AUC) of the model including LHAP were significantly higher than that of models including both albumin and Hgb. LHAP best cut-off value for the development of CI-AKI was 9.26 (sensitivity 68% and specificity 66%).ConclusionLHAP values were the most important predictor of CI-AKI, followed by creatinine value and Killip class. LHAP values are significantly associated with CI-AKI after p-PCI.
- Journal
- ACTA CARDIOLOGICA
- Year
- 2023
- Volume
- 78
- Issue
- 8
- Pages
- 901-909
- ISSN
- 0001-5385
- eISSN
- 1784-973X
- DOI
- 10.1080/00015385.2023.2187126
- WoS UID
- WOS:000951054900001