language Türkçe
Article 2023 · 30 citations

Analysis of Phenolic Compounds by LC-HRMS and Determination of Antioxidant and Enzyme Inhibitory Properties of <i>Verbascum speciousum</i> Schrad

Kiziltas, Hatice, Bingol, Zeynebe, Goren, Ahmet C., Alwasel, Saleh H., Gulcin, Ilhami

Abstract

Studies have shown an inverse correlation between age-related illnesses like coronary heart disease and cancer and fruit and vegetable intake. Given the probable health benefits of natural antioxidants from plants, research on them has increased. Verbascum L is a large genus of Scrophulariaceae family and 323 species distributed worldwide. Since Verbascum L. species are plants that are grown in many regions of Turkiye and are used in folk medicine, it is important to evaluate the biological activity of these species. In this study antioxidant properties of Verbascum speciosum Schrad. were investigated. The antioxidant capacities of water and ethanol-based extracts obtained from air parts were evaluated with Fe3+ reducing, CUPRAC, FRAP, DPPH center dot, and ABTS(center dot+) scavenging antioxidant methods. Extracts were also examined to determine their AChE, alpha-glycosidase and alpha-amylase enzyme inhibitions. This investigation could be a basis for further phytochemical investigations of Verbascum speciosum Schrad.

Keywords
Verbascum speciosum antioxidant activity reducing power radical scavenging enzyme inhibition IN-VITRO ANTIOXIDANT RADICAL SCAVENGING ACTIVITIES CARBONIC-ANHYDRASE ANTIRADICAL ACTIVITIES CRYSTAL-STRUCTURE CAFFEIC ACID ACETYLCHOLINESTERASE DERIVATIVES EXTRACT BUTYRYLCHOLINESTERASE
WoS Categories
Plant Sciences Chemistry, Applied Chemistry, Medicinal
Sustainable Development Goals
Citation
Journal
RECORDS OF NATURAL PRODUCTS
Year
2023
Volume
17
Issue
3
Pages
485-500
ISSN
1307-6167
DOI
10.25135/rnp.370.2210.2598
WoS UID
WOS:000922592600001
Open via DOI