Article
2022
·
5 citations
Synthesis and reactions of di(thiophen-2-yl)alkane diones: Cyclocondensation
Abstract
Known 1,6-di(thiophen-2-yl)hexane-1,6-dione (2) and novel 1,7-di(thiophen-2-yl)heptane-1,7-dione (4) were obtained from the reactions of thiophene with the corresponding diacyl chlorides. Furthermore, compounds with furan and pyrrole units in place of thiophene units in compound 2 were obtained in the same way. Bromination of 2 and 4 gave bromides regioselectively. The reaction of each of the compounds 2 and 4 in HOAc medium yielded cyclocondensation products. In total, four known and eleven novel compounds were synthesized.
Keywords
Acylation
bromination
cyclocondensation
diketone
thiophene
1ST SYNTHESIS
DERIVATIVES
THIOPHENE
BROMOPHENOLS
BROMINATION
WoS Categories
Chemistry, Multidisciplinary
Engineering, Chemical
Sustainable Development Goals
Citation
- Journal
- TURKISH JOURNAL OF CHEMISTRY
- Year
- 2022
- Volume
- 46
- Issue
- 5
- Pages
- 1397-+
- ISSN
- 1300-0527
- DOI
- 10.55730/1300-0527.3446
- WoS UID
- WOS:000876350600004