Article 2022 · 3 citations

Macroporous Surgical Mesh from a Natural Cocoon Composite

Chen, Yong-Ming, Zang, Lian-Sheng, Koc-Bilican, Behlul, Bilican, Ismail, Holland, Chris, Cansaran-Duman, Demet, Karaduman, Tugce, Colak, Arzu, Bayir, Yasin, Halici, Zekai, Ozmen, Sevilay, Ali, Asad, Labidi, Jalel, Elbuken, Caglar, Kaya, Murat

Abstract

Recently, traditional polymer-based surgical mesheshave drawn unwanted attention as a result of host tissuecomplications arising from infection, biocompatibility, andmechanical compatibility. Seeking an alternative solution, wepresent a hierarchically structured nanofibrous surgical meshderived from the naturally woven cocoon of the Japanese giantsilkworm, termed MothMesh. We report that it displays non-toxicity, biocompatibility, suitable mechanical properties, andporosity while showing no adverse effect in animal trials andeven appears to enhance cell proliferation. Hence, we assert thatthe use of this natural material may provide an effective andimproved alternative to existing synthetic meshes

Keywords

sustainable material fibroin sericin biocompatibility surgical mesh tissue engineering SILK FIBROIN SCAFFOLD ABDOMINAL-WALL HERNIA REPAIR ENZYMATIC DEGRADATION MECHANICAL-PROPERTIES CELL-ADHESION SERICIN BIODEGRADATION RECONSTRUCTION BIOMATERIALS

WoS Categories

Chemistry, Multidisciplinary Green & Sustainable Science & Technology Engineering, Chemical

Sustainable Development Goals

Good Health and Well-being

Citation

Journal: ACS SUSTAINABLE CHEMISTRY & ENGINEERING
Year: 2022
Volume: 10
Issue: 18
Pages: 5728-5738
ISSN: 2168-0485
DOI: 10.1021/acssuschemeng.1c06941
WoS UID: WOS:000800521700004

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