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Article 2022 · 115 citations

Management of granulomatous lobular mastitis: an international multidisciplinary consensus (2021 edition)

Yuan, Qian-Qian, Xiao, Shu-Xuan, Farouk, Omar, Du, Yu-Tang, Sheybani, Fereshte, Tan, Qing Ting, Akbulut, Sami, Cetin, Kenan, Alikhassi, Afsaneh, Yaghan, Rami Jalal, Durur-Subasi, Irmak, Altintoprak, Fatih, Eom, Tae Ik, Alper, Fatih, Hasbahceci, Mustafa, Martinez-Ramos, David, Oztekin, Pelin Seher, Kwong, Ava, Pluguez-Turull, Cedric W., Brownson, Kirstyn E., Chandanwale, Shirish, Habibi, Mehran, Lan, Liu-Yi, Zhou, Rui, Zeng, Xian-Tao, Bai, Jiao, Bai, Jun-Wen, Chen, Qiong-Rong, Chen, Xing, Zha, Xiao-Ming, Dai, Wen-Jie, Dai, Zhi-Jun, Feng, Qin-Yu, Gao, Qing-Jun, Gao, Run-Fang, Han, Bao-San, Hou, Jin-Xuan, Hou, Wei, Liao, Hai-Ying, Luo, Hong, Liu, Zheng-Ren, Lu, Jing-Hua, Luo, Bin, Ma, Xiao-Peng, Qian, Jun, Qin, Jian-Yong, Wei, Wei, Wei, Gang, Xu, Li-Ying, Xue, Hui-Chao, Yang, Hua-Wei, Yang, Wei-Ge, Zhang, Chao-Jie, Zhang, Fan, Zhang, Guan-Xin, Zhang, Shao-Kun, Zhang, Shu-Qun, Zhang, Ye-Qiang, Zhang, Yue-Peng, Zhang, Sheng-Chu, Zhao, Dai-Wei, Zheng, Xiang-Min, Zheng, Le-Wei, Xu, Gao-Ran, Zhou, Wen-Bo, Wu, Gao-Song

Abstract

Granulomatous lobular mastitis (GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care for patients with inflammatory disorders of the breast. This consensus is summarized to establish evidence-based recommendations for the management of GLM. Literature was reviewed using PubMed from January 1, 1971 to July 31, 2020. Sixty-six international experienced multidisciplinary experts from 11 countries or regions were invited to review the evidence. Levels of evidence were determined using the American College of Physicians grading system, and recommendations were discussed until consensus. Experts discussed and concluded 30 recommendations on historical definitions, etiology and predisposing factors, diagnosis criteria, treatment, clinical stages, relapse and recurrence of GLM. GLM was recommended as a widely accepted definition. In addition, this consensus introduced a new clinical stages and management algorithm for GLM to provide individual treatment strategies. In conclusion, diagnosis of GLM depends on a combination of history, clinical manifestations, imaging examinations, laboratory examinations and pathology. The approach to treatment of GLM should be applied according to the different clinical stage of GLM. This evidence-based consensus would be valuable to assist front-line surgeons and medical specialists in the optimal management of GLM.

Keywords
Granulomatous mastitis Granulomatous lobular mastitis Idiopathic granulomatous mastitis Diagnosis Treatment CORYNEBACTERIUM ASSOCIATION RECURRENCE DIAGNOSIS METHOTREXATE EXPERIENCE FEATURES STEROIDS THERAPY
WoS Categories
Medicine, General & Internal
Sustainable Development Goals
Citation
Journal
MILITARY MEDICAL RESEARCH
Year
2022
Volume
9
Issue
1
ISSN
2095-7467
eISSN
2054-9369
DOI
10.1186/s40779-022-00380-5
WoS UID
WOS:000787756900001
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