Exploiting Urazole's Acidity for Fabrication of Hydrogels and Ion-Exchange Materials
Hanay, Saltuk B., Fallah, Ali, Senturk, Efsun, Yetim, Zeliha, Afghah, Ferdows, Yilmaz, Hulya, Culha, Mustafa, Koc, Bahattin, Zarrabi, Ali, Varma, Rajender S.
In this study, the acidity of urazole (pKa 5-6) was exploited to fabricate a hydrogel in two simple and scalable steps. Commercially available poly(hexamethylene)diisocyanate was used as a precursor to synthesize an urazole containing gel. The formation of urazole was confirmed by FT-IR and H-1-NMR spectroscopy. The hydrogel was characterized by microscopy imaging as well as spectroscopic and thermo-gravimetric analyses. Mechanical analysis and cell viability tests were performed for its initial biocompatibility evaluation. The prepared hydrogel is a highly porous hydrogel with a Young's modulus of 0.91 MPa, has a swelling ratio of 87%, and is capable of exchanging ions in a medium. Finally, a general strategy was demonstrated to embed urazole groups directly into a crosslinked material.
- Journal
- GELS
- Year
- 2021
- Volume
- 7
- Issue
- 4
- eISSN
- 2310-2861
- DOI
- 10.3390/gels7040261
- WoS UID
- WOS:000737620100001