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Article 2021 · 18 citations

Managing adult patients with infectious diseases in emergency departments: international ID-IRI study

Erdem, Hakan, Hargreaves, Sally, Ankarali, Handan, Caskurlu, Hulya, Ceviker, Sevil Alkan, Bahar-Kacmaz, Asiye, Meric-Koc, Meliha, Altindis, Mustafa, Yildiz-Kirazaldi, Yasemin, Kizilates, Filiz, Alsalman, Jameela, Cag, Yasemin, Kamal, Abu Hena Mostafa, Dokmetas, Ilyas, Dindar-Demiray, Emine Kubra, Shehata, Ghaydaa Ahmed, Hasman, Hakan, Sadykova, Ainur, Llopis, Ferran, Ramosaco, Ergys, Logar, Mateja, Alay, Handan, Kesmez-Can, Fatma, Ruch, Yvon, Bulut, Dilek, Makek, Mateja Jankovic, Marino, Andrea, Mahboob, Amjad, El-Kholy, Amani, Abdallah, Dirar, Sefa-Sayar, Merve, Karaali, Ridvan, Aslan, Selda, Dar, Razi Even, Abdalla, Esam, Monzon-Camps, Helena, Baljic, Rusmir, Mgdalena, Dumitru Irina, Naghili, Behrouz, Abbas Dafalla, Mohamed Elhassan, Alwashmi, Ameen S. S., Carmen, Cernat Roxana, Ramirez-Estrada, Sergio, Wojewodzka-Zelezniakowicz, Marzena, Akyildiz, Ozay, Zajkowska, Joanna, El-Sokkary, Rehab, Pandya, Nirav, Amer, Fatma, Alavi-Darazam, Ilad, Grgic, Svjetlana, Wegdan, Ahmed Ashraf, El-Kholy, Jehan, Bulut-Avsar, Cansu, Kulzhanova, Sholpan, Tasbakan, Meltem, Kumari, Hema Prakash, Dirani, Natalia, Koganti, Kalyan, Konkayev, Aidos K., Petrov, Michael M., Cascio, Antonio, Liskova, Anna, Del Vecchio, Rosa Fontana, Lambertenghi, Lorenza, Mladenov, Nikolay, Oncu, Serkan, Rello, Jordi

Abstract

We aimed to explore factors for optimizing antimicrobial treatment in emergency departments. A single-day point prevalence survey was conducted on January 18, 2020, in 53 referral/tertiary hospitals in 22 countries. 1957 (17%) of 11557 patients presenting to EDs had infections. The mean qSOFA score was 0.37 +/- 0.74. Sepsis (qSOFA >= 2) was recorded in 218 (11.1%) patients. The mean qSOFA score was significantly higher in low-middle (1.48 +/- 0.963) compared to upper-middle (0.17 +/- 0.482) and high-income (0.36 +/- 0.714) countries ( P < 0.001). Eight (3.7%) patients with sepsis were treated as outpatients. The most common diagnoses were upper-respiratory (n = 877, 43.3%), lower-respiratory (n = 316, 16.1%), and lower-urinary (n = 201, 10.3%) infections. 1085 (55.4%) patients received antibiotics. The most-commonly used antibiotics were beta-lactam (BL) and BL inhibitors (n = 307, 15.7%), third-generation cephalosporins (n = 251, 12.8%), and quinolones (n = 204, 10.5%). Irrational antibiotic use and inappropriate hospitalization decisions seemed possible. Patients were more septic in countries with limited resources. Hence, a better organizational scheme is required.

Keywords
Emergency infection sepsis treatment antibiotic elderly SEPSIS
WoS Categories
Oncology Infectious Diseases Pathology Pharmacology & Pharmacy
Sustainable Development Goals
Citation
Journal
JOURNAL OF CHEMOTHERAPY
Year
2021
Volume
33
Issue
5
Pages
302-318
ISSN
1120-009X
eISSN
1973-9478
DOI
10.1080/1120009X.2020.1863696
WoS UID
WOS:000630391700001
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