Article 2021 · 5 citations

Determination of natural phenolic compounds of <i>Ferula longipedunculata</i> Pesmen and assessment their antioxidant and anticholinesterase potentials

Karakaya, Songul, Koca, Mehmet, Sytar, Oksana, Duman, Hayri

Abstract

The paper reports anticholinesterase and antioxidant activities of extracts, fractions from aerial parts, roots, flowers, fruits of Ferula longipedunculata Pesmen (Apiaceae). Phenolic content, antioxidant activities of samples were carried out using Folin-Ciocalteu, DPPH, TBA methods. Anticholinesterase activity was actualised through Ellman's method. The utmost and least total phenolic content were detected in root MeOH extract (36.4 mg GAE g(-1) DW) and aerial part (23.74 mg GAE g(-1) DW), respectively. Hexane fraction of root exhibited significant inhibition against AChE (37.99%) and BuChE (81.66%) at 20 mu g/mL as well as remarkable antioxidant and anticholinesterase activities. However, investigations on roots will be substantial for improved usage of F. longipedunculata for pharmaceutical and food search needs.

Keywords

Antioxidants anticholinesterase Apiaceae Ferula longipedunculata phenolics INHIBITORS COUMARINS

WoS Categories

Chemistry, Applied Chemistry, Medicinal

Sustainable Development Goals

Good Health and Well-being

Citation

Journal: NATURAL PRODUCT RESEARCH
Year: 2021
Volume: 35
Issue: 10
Pages: 1654-1656
ISSN: 1478-6419
eISSN: 1478-6427
DOI: 10.1080/14786419.2019.1619728
WoS UID: WOS:000471515400001

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