Article Early Access 2025 · 1 atıf

The first detection of Jingmen tick virus (JMTV) in humans in Türkiye, 2022

Oz, Murtaza, Dincer, Ender, Pektas, Ayse Nur, Timurkan, Mehmet Ozkan, Bagci, Binnur, Tasseten, Tuba Nur, Cakir Kiymaz, Yasemin, Buyuktuna, Seyit Ali, Bakir, Mehmet, Elaldi, Nazif

Özet

Jingmen tick virus (JMTV) is a single-stranded RNA virus transmitted to humans through tick bites and classified within the Flaviviridae family. It has been detected in various arthropods and mammals. JMTV causes an acute febrile illness with symptoms such as skin lesions, fatigue, headache, nausea, and vomiting; however, limited research exists on its clinical impact and pathogenesis in humans. This study aims to report the first detection and molecular characterization of JMTV in patients with Crimean-Congo Hemorrhagic Fever (CCHF) in T & uuml;rkiye. During the 2022 outbreak, serum samples from 206 hospitalized CCHF-suspected patients were retrospectively analyzed. JMTV was identified in 3 (1.5%) cases using nested PCR. The nucleotide similarity within the three JMTV sequences was found to be between 98.0% and 99.0%. Phylogenetic analysis showed 82-98% similarity with previously identified JMTV isolates in T & uuml;rkiye. This study presents the first detection and molecular characterization of JMTV in humans in T & uuml;rkiye. Clinicians should consider JMTV in patients with a history of tick bites, especially in CCHF-endemic regions.

Anahtar Kelimeler

Jingmen tick virus nested-PCR sequencing segment 1 gene human MANAGEMENT

WoS Kategorileri

Public, Environmental & Occupational Health Parasitology Tropical Medicine

Sürdürülebilir Kalkınma Amaçları

Sağlık ve Kaliteli Yaşam

Künye

Dergi: PATHOGENS AND GLOBAL HEALTH
Yıl: 2025
ISSN: 2047-7724
eISSN: 2047-7732
DOI: 10.1080/20477724.2025.2603234
WoS UID: WOS:001637837900001

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