Article 2026 · 1 atıf

Water-soluble exopolysaccharide of Niallia circulans BP13 exhibits antioxidant, wound healing, skin anti-aging and anticancer activities

Albayrak, Seyda, Aykutoglu, Gurkan, Adiguzel, Gulsah, Adiguzel, Ahmet, Arslan, Nazli Pinar, Onder, Saadet Hilal, Taskin, Mesut

Özet

Microbial exopolysaccharides have different applications in food, cosmetic, pharmaceutical and nutraceutical industries owing to their bioactive properties. This study was undertaken to characterize the exopolysaccharide (EPS) from Niallia circulans BP13 (GenBank: PP268015) and to evaluate its biological activities. The exopolysaccharide was determined to be a water-soluble heteropolysaccharide with low molecular weight, composed of different monomers, mainly galactose. The exopolysaccharide displayed in vitro antioxidant, wound healing and antiskin-aging activites. Furthermore, EPS was determined to exert dose-dependent anticancer effects on lung, colon, neuroblastoma and prostate cancer cell lines. This is the first attempt to determine the in vitro wound healing and antiskin-aging activities of N. circulans-derived EPS. Owing to these beneficial biological activities, EPS may find applications in the cosmetic and pharmaceutical industries.

Anahtar Kelimeler

bacteria polysaccharide characterization biological activity wound healing POLYSACCHARIDES

WoS Kategorileri

Biotechnology & Applied Microbiology Energy & Fuels

Sürdürülebilir Kalkınma Amaçları

Sağlık ve Kaliteli Yaşam

Künye

Dergi: BIOFUELS BIOPRODUCTS & BIOREFINING-BIOFPR
Yıl: 2026
Cilt: 20
Sayı: 2
Sayfa: 717-732
ISSN: 1932-104X
eISSN: 1932-1031
DOI: 10.1002/bbb.70099
WoS UID: WOS:001630851300001

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