Article 2025 · 0 atıf

Association between higher morning preference and better health-related quality of life in asthma

Patel, Neel, Deprato, Andy, Qian, Tina, Adan, Ana, Akgueuron, Metin, Anderson, Augustus, Brickstock, Amanda, Eathorne, Allie, Garud, Arundhati, Haldar, Prasun, Jindal, Aditya, Jindal, Surinder Kumar, Kerget, Bugra, Moitra, Saibal, Mukherjee, Rahul, Semprini, Alex, Turner, Alice M., Murgia, Nicola, Lacy, Paige, Moitra, Subhabrata

Özet

Background: Circadian preference for eveningness has been linked to a higher risk of asthma and allergies, but its association with health-related quality of life (HRQL) in asthma has not been studied yet. Objective: We aimed to investigate the associations between individual circadian preference and HRQL in asthma. Methods: Among 691 adult asthma patients from Canada, India, New Zealand, and the United Kingdom, a digital questionnaire was administered to capture demographic information, social and psychologic attributes, comorbidities, and medication adherence. Circadian preference and HRQL were assessed by the reduced version of the morningness-eveningness questionnaire (rMEQ) and the short form of the chronic respiratory questionnaire, respectively. We analyzed the association between chronotype and HRQL using mixed-effect linear regression models. Results: Of all participants, 59% were female with a mean (standard deviation) age of 49 (17) years. Median (interquartile range) rMEQ total score was 17 (14-19). Mean (standard deviation) dyspnea, fatigue, emotional function, and mastery scores were 5.94 (1.2), 4.38 (1.3), 5.05 (1.3), and 1.96 (1.1), respectively. In regression analysis, a higher rMEQ total score (higher morningness) was associated with less fatigue ((3 = 0.06; 95% confidence interval, 0.04 to 0.09) and better emotional function ((3 = 0.03; 95% confidence interval, 0.004 to 0.06), and these associations were mediated by less anxiety, depression, and alcohol abuse, and better sleep quality. Conclusion: Morning orientation is associated with better HRQL in patients with asthma. The results suggest that working with patients to promote schedules and habits related to morningness may be beneficial. (J Allergy Clin Immunol Global 2025;4:100456.)

Anahtar Kelimeler

Anxiety alcohol chronotype depression morningness SF-CRQ sleep GENDER-DIFFERENCES PHYSICAL-ACTIVITY SEX-DIFFERENCES EVENINGNESS ADULTS SLEEP CHRONOTYPE

WoS Kategorileri

Allergy Immunology

Sürdürülebilir Kalkınma Amaçları

Sağlık ve Kaliteli Yaşam

Künye

Dergi: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY: GLOBAL
Yıl: 2025
Cilt: 4
Sayı: 2
eISSN: 2772-8293
DOI: 10.1016/j.jacig.2025.100456
WoS UID: WOS:001463915000001

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