Review 2024 · 0 atıf

Transcranial Magnetic Stimulation in Alcohol Use Disorder Treatment: A Narrative Review

Özet

Alcohol use disorder is a mental health problem characterized by symptoms such as withdrawal, tolerance, and intense alcohol craving, affecting approximately 8.5% of the global adult population. Non-invasive neuromodulation techniques like repetitive transcranial magnetic stimulation are gaining interest in alcohol use disorder treatment. This review aimed to assess the efficacy of repetitive transcranial magnetic stimulation, deep transcranial magnetic stimulation, and theta burst stimulation protocols in treating alcohol use disorder, focusing on randomized controlled studies with sham. The studies reviewed predominantly target the dorsolateral prefrontal cortex. Some repetitive transcranial magnetic stimulation protocols have shown positive effects on reducing craving and improving cognitive functions, while others did not find significant clinical changes. The results of deep transcranial magnetic stimulation studies targeting the medial prefrontal cortex and anterior cingulate cortex also vary; some report reductions in alcohol consumption, while others do not demonstrate significant effects. Theta burst stimulation studies suggest that particularly intermittent theta burst stimulation protocols may be effective in reducing depressive symptoms and relapse risk, whereas continuous theta burst stimulation protocols tend to have shorter and more limited effects. In conclusion, the efficacy of repetitive transcranial magnetic stimulation in the treatment of alcohol use disorder varies according to the targeted brain region, stimulation parameters, and patient characteristics. There is a need for studies with larger sample sizes, homogeneous protocols, and long-term follow-ups to more clearly define the role of repetitive transcranial magnetic stimulation in alcohol use disorder treatment.

Anahtar Kelimeler

Alcohol use disorder craving repetitive transcranial magnetic stimulation THETA-BURST STIMULATION PREFRONTAL CORTEX DEPENDENT PATIENTS COCAINE USERS RTMS ADDICTION TMS VETERANS EFFICACY PILOT

WoS Kategorileri

Substance Abuse

Sürdürülebilir Kalkınma Amaçları

Sağlık ve Kaliteli Yaşam

Künye

Dergi: ADDICTA-THE TURKISH JOURNAL ON ADDICTIONS
Yıl: 2024
Cilt: 11
Sayı: 3
Sayfa: 388-399
ISSN: 2148-7286
eISSN: 2149-1305
DOI: 10.5152/ADDICTA.2024.24213
WoS UID: WOS:001447350700019

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