Article 2024 · 1 atıf

Selectfluor and alcohol-mediated synthesis of bicyclic oxyfluorination compounds by Wagner-Meerwein rearrangement

Dagalan, Ziya, Celikoglu, Muhammed Hanifi, Celik, Saffet, Kocak, Ramazan, Nisanc, Bilal

Özet

Herein, we report the first environmentally friendly systematic fluoroalkoxylation reactions in bicyclic systems. New oxyfluorination products were obtained with excellent yields (up to 98%) via Wagner-Meerwein rearrangement using benzonorbornadiene and the chiral natural compound (+)-camphene as bicyclic alkenes, selectfluor as an electrophilic fluorine source, and water and various alcohols as nucleophile sources. The structure of bicyclic oxy- and alkoxyfluorine compounds was determined by NMR and QTOFMS analyses.

Anahtar Kelimeler

alkoxyfluorine compounds bicyclic alkene oxyfluorination selectfluor Wagner-Meerwein rearrangement FLUORINATION MILD

WoS Kategorileri

Chemistry, Organic

Sürdürülebilir Kalkınma Amaçları

İklim Eylemi Sağlık ve Kaliteli Yaşam

Künye

Dergi: BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Yıl: 2024
Cilt: 20
Sayfa: 1462-1467
ISSN: 1860-5397
DOI: 10.3762/bjoc.20.129
WoS UID: WOS:001260328600001

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