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Article 2025 · 2 atıf

Boric Acid in Milk Replacer as a Health Enhancer and Growth Promoter for Lambs in the Suckling Period

Uysal, Soner, Yoruk, Mehmet Akif

Özet

This study was performed to investigate the effects of boric acid supplementation in milk replacer of lambs in the suckling period on performance, biochemical parameters, the antioxidant system, fecal culture, and expression of some genes. During the suckling period, 60 lambs (4 days old) were randomly given four levels of boric acid (0, 30, 60, and 90 mg/kg body weight) via milk replacer for 57 days. The lambs supplemented with boric acid had a higher weight gain and better feed conversion ratio. Boric acid supplementation quadratically increased serum triglyceride, total protein, alkaline phosphatase, serum antioxidant activity and oxidative stress biomarkers, and fecal flora and decreased IL1 beta, IL10, iNOS, NF-kB, and TNF-alpha gene expressions. The effect of boric acid on rumen papilla development could not be determined since the animals were not slaughtered. In conclusion, the use of boric acid to lambs in the suckling period improved the average weekly body weight gain and feed conversion efficiency, positively affected some biochemical parameters, antioxidant system, and intestinal flora, and also affected gene expressions related to the immune system. Boric acid supplementation had a beneficial effect on the health and growth of suckling lambs.

Anahtar Kelimeler
Boric acid Lamb health Immune system Suckling period Gene expressions BORON SUPPLEMENTATION OXIDATIVE STRESS PARAMETERS PERFORMANCE INFLAMMATION APOPTOSIS RESPONSES CALCIUM ELEMENT IMMUNE
WoS Kategorileri
Biochemistry & Molecular Biology Endocrinology & Metabolism
Sürdürülebilir Kalkınma Amaçları
Künye
Dergi
BIOLOGICAL TRACE ELEMENT RESEARCH
Yıl
2025
Cilt
203
Sayı
2
Sayfa
850-860
ISSN
0163-4984
eISSN
1559-0720
DOI
10.1007/s12011-024-04214-4
WoS UID
WOS:001226531600002
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