Article 2023 · 4 atıf

Stereotactic radiosurgery for tumors of the pineal region: A single-center experience

Zeynal, Mete, Karaaslan, Burak, Dagli, Ozlem, Borcek, Alp, Kurt, Goekhan, Kadioglu, Hakan Hadi, Emmez, Omer Hakan

Özet

Tumors of the pineal region (TPRs) are rare neoplasms that are surgically challenging to resect. Conventional treatment strategies are available, but gamma knife radiosurgery (GKRS) is an alternative approach. This study presents a single-center experience with GKRS performed for TPR with and without histopathological diagnoses. The cases of 25 patients with TPRs treated with GKRS were retrospectively analyzed. Thirteen of these 25 patients had histopathological confirmation, and 13 had elevated serum alpha-fetoprotein and beta-human chorionic gonadotropin levels. The 25 patients had a mean follow-up duration of 61 months. The total response rate to GKRS was 60%, and a 53.8% decrease in the alpha-fetoprotein and beta human chorionic gonadotropin levels was observed. The findings of this study indicate that GKRS is a safe procedure for TPRs, even in the event of insufficient histopathological findings. This treatment approach provides increased Karnofsky performance scores and an extended life expectancy.

Anahtar Kelimeler

germ cell tumors pineal tumors pineocytoma radiosurgery MANAGEMENT DIAGNOSIS

WoS Kategorileri

Medicine, General & Internal

Sürdürülebilir Kalkınma Amaçları

Sağlık ve Kaliteli Yaşam

Künye

Dergi: MEDICINE
Yıl: 2023
Cilt: 102
Sayı: 27
ISSN: 0025-7974
eISSN: 1536-5964
DOI: 10.1097/MD.0000000000034005
WoS UID: WOS:001025647200003

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