Article 2023 · 3 atıf

Assessment of fibrinogen albumin ratio in patients with pregnancy-related cerebral venous thrombosis

Özet

Introduction and objectiveCerebral venous thrombosis (CVT) is a cerebrovascular disease observed more commonly in women of childbearing age. There is currently no biomarker used to predict the risk of CVT during the follow-up of pregnant/postpartum patients. In this context, the objective of this study is to investigate the importance of fibrinogen and albumin levels and fibrinogen-to-albumin ratio (FAR) values, which predispose to thromboembolism, in pregnant/postpartum patients.Material and methodThe study sample consisted of 19 pregnant/postpartum patients with a diagnosis of CVT, 20 pregnant/postpartum patients without CVT. Albumin and fibrinogen levels and FAR values were compared between these two groups.ResultsFibrinogen level was significantly higher in pregnant/postpartum CVT patients compared to pregnant/postpartum patients without CVT (p = 0.010). On the other hand, albumin level was significantly lower in pregnant/postpartum CVT patients compared to the other group (p = 0.010). Lastly, FAR level was significantly higher in pregnant/postpartum CVT patients compared to the other group (p = 0.011). There was no correlation between FAR values and modified Rankin score.ConclusionThe study findings indicated that high fibrinogen and low albumin levels and high FAR values are associated with an increased risk of CVT in pregnant/postpartum patients.

Anahtar Kelimeler

Fibrinogen Albumin Pregnancy Cerebral venous thrombosis CORONARY-ARTERY-DISEASE SINUS THROMBOSIS PUERPERIUM SEVERITY THERAPY DIMER

WoS Kategorileri

Clinical Neurology Neurosciences

Künye

Dergi: ACTA NEUROLOGICA BELGICA
Yıl: 2023
Cilt: 123
Sayı: 6
Sayfa: 2251-2258
ISSN: 0300-9009
eISSN: 2240-2993
DOI: 10.1007/s13760-023-02294-y
WoS UID: WOS:000992351100002

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