Review 2023 · 4 atıf

Incorporation of Protecting Groups in Organic Chemistry: A Mini-Review

Kisla, Mehmet Murat, Hassan, Mohammed Al-Kassim, Osman, Hind M., Aydin, Amine Sena, Sen, Hasan Tahsin, Khazei, Shan, Kul, Pinar, Kus, Canan

Özet

The approach of utilizing protecting groups (PGs) in organic chemistry has led to the successful syntheses of an array of useful organic compounds. This strategy has also addressed some of the complexities associated with many organic reactions. These PGs find useful applications in simple and complex reactions that involve the synthesis of large organic compounds such as peptides, and oligosaccharides. The fundamental role of PGs is to prevent undesired reactions that could hinder the progress or completion of such reactions. Ideal PGs must be utilized in this regard to achieve the desired objectives. This review describes the diverse protecting groups found in the literatures, the functional moieties for the protection, deprotection strategies, and their relevant applications in organic synthesis.

Anahtar Kelimeler

Protecting groups deprotection functional group organic synthesis side reactions oligosaccharides PHASE PEPTIDE-SYNTHESIS EFFICIENT SYNTHESIS OLIGONUCLEOTIDES DEPROTECTION MACROCYCLIZATION CONSTRUCTION STRATEGIES RAPAMYCIN REAGENT TAXOL

WoS Kategorileri

Chemistry, Organic

Sürdürülebilir Kalkınma Amaçları

Sağlık ve Kaliteli Yaşam

Künye

Dergi: CURRENT ORGANIC SYNTHESIS
Yıl: 2023
Cilt: 20
Sayı: 5
Sayfa: 491-503
ISSN: 1570-1794
eISSN: 1875-6271
DOI: 10.2174/1570179419666220820152723
WoS UID: WOS:000990978700001

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