Article 2022 · 16 atıf

The effect of evening primrose oil (<i>Oenothera biennis</i>) on the level of adiponectin and some biochemical parameters in rats with fructose induced metabolic syndrome

Mert, Handan, Irak, Kivanc, Cibuk, Salih, Yildirim, Serkan, Mert, Nihat

Özet

The effect of evening primrose oil on adiponectin level and some biochemical parameters in model of fructose-induced metabolic syndrome were investigated. The rats were divided into 4 groups: control, evening primrose oil, fructose, fructose + evening primrose oil. Body weight, daily feed and water consumptions and systolic blood pressures of animals were measured. At the end of trial, blood samples were taken, livers were excised and histopathological examination was performed. Glucose, uric acid, triglyceride, T.cholesterol, LDL, HDL, VLDL, ALT, AST, ALP, LDH, adiponectin, insulin, IL-6, TNF-alpha, TAC, and TOS levels were analysed. Some analysed parameters and systolic blood pressure of fructose + evening primrose oil group decreased significantly compared to fructose group and adiponectin, TAC, and HDL levels were significantly increased. As conclusion, evening primrose oil can be considered as antioxidant agent by reducing oxidative stress, increasing adiponectin levels and insulin sensitivity, anti-inflammatory properties, exhibiting anti-atherogenic effect by regulating dyslipidemia and systolic blood pressure.

Anahtar Kelimeler

Metabolic syndrome fructose evening primrose oil adiponectin oxidant-antioxidant status INDUCED INSULIN-RESISTANCE ADIPOSE-SPECIFIC PROTEIN FATTY LIVER-DISEASE OXIDATIVE STRESS CONSUMPTION EXPRESSION INFLAMMATION TISSUE MODEL HYPERTENSION

WoS Kategorileri

Biochemistry & Molecular Biology Biophysics Endocrinology & Metabolism Physiology

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Sağlık ve Kaliteli Yaşam

Künye

Dergi: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
Yıl: 2022
Cilt: 128
Sayı: 6
Sayfa: 1539-1547
ISSN: 1381-3455
eISSN: 1744-4160
DOI: 10.1080/13813455.2020.1781900
WoS UID: WOS:000549473700001

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