Mardinoglu, Adil

OncoRisk: a state-of-the-art web server for bridging the oncogenic databases and pan-cancer cohorts to the translational oncology

Machine learning identifies proteomic risk factors across 23 diseases

The Human Pathology Atlas for deciphering the prognostic features of human cancers

Synthesis of novel tetrahydrobenzo[b]thiophene-3-carbonitrile (THBTC)-based heterocycles: Structural insights, reactivity profiles, and in-silico bioactivity studies

A human pan-disease blood atlas of the circulating proteome

Targeting PKLR in liver diseases

Unravelling the Complexity of Sarcopenia Through a Systems Biology Approach

Longitudinal big biological data in the AI era

Anticancer effects and mechanisms of Pulsatilla chinensis, Bupleurum chinense and Polyporus umbellatus on human lung carcinoma and hepatoma cells

Integrative proteo-transcriptomic characterization of advanced fibrosis in chronic liver disease across etiologies

Synthesis and Characterization of Memantine-Loaded Niosomes for Enhanced Alzheimer's Disease Targeting

Design, Synthesis, and Computational Evaluation of 3,4-Dihydroquinolin-2(<i>1H</i>)-One Analogues as Potential VEGFR2 Inhibitors in Glioblastoma Multiforme

Synthesis and biological assessment of BUB1B inhibitors for the treatment of clear cell renal cell carcinoma

Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats

Multi-omics characterization of improved cognitive functions in Parkinson's disease patients after the combined metabolic activator treatment: a randomized, double-blinded, placebo-controlled phase II trial

Synthesis, Characterization, Theoretical Studies and in Vitro Embriyotoxic, Genotoxic and Anticancer Effects of Novel Phenyl(1,4,6-Triphenyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidin-5-yl)Methanone

Synthesis and Biological Evaluation of Novel Benzylidene Thiazolo Pyrimidin-3(5<i>H</i>)-One Derivatives

Identification of <i>SPP1</i><SUP>+</SUP> macrophages as an immune suppressor in hepatocellular carcinoma using single-cell and bulk transcriptomics

Identifying Hub Genes and Metabolic Pathways in Collagen VI-Related Dystrophies: A Roadmap to Therapeutic Intervention

Targeting Alzheimer's disease with novel dual-function 3,5-diaryl-4,5-dihydro-1H-pyrazole-1-carbothioamide derivatives

Unveiling the Molecular Mechanisms of Glioblastoma through an Integrated Network-Based Approach

Multi-omics analysis reveals the key factors involved in the severity of the Alzheimer's disease

Discovery of Cell-Permeable Allosteric Inhibitors of Liver Pyruvate Kinase: Design and Synthesis of Sulfone-Based Urolithins

Discovery of a Therapeutic Agent for Glioblastoma Using a Systems Biology-Based Drug Repositioning Approach

Design and evaluation of novel inhibitors for the treatment of clear cell renal cell carcinoma

Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning ( vol 83 , 104214 , 2022)

Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases (Retraction of Vol 314, art no 121325, 2023)

Unveiling structural features, chemical reactivity, and bioactivity of a newly synthesized purine derivative through crystallography and computational approaches

Synthesis, spectroscopic characterization, DFT and molecular docking of N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl) naphthalene-1-sulfonamide derivatives

Design and synthesis of novel JNK inhibitors targeting liver pyruvate kinase for the treatment of non-alcoholic fatty liver disease and hepatocellular carcinoma

Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases

In Vitro Cytotoxic, Genotoxic, Embryotoxic and Oxidative Damage Potentials by Empagliflozin

Anticancer Potential of Novel Cinnamoyl Derivatives against U87MG and SHSY-5Y Cell Lines

Drug Synergism of Anticancer Action in Combination with Favipiravir and Paclitaxel on Neuroblastoma Cells

Boric Acid and Borax Protect Human Lymphocytes from Oxidative Stress and Genotoxicity Induced by 3-Monochloropropane-1,2-diol

Novel tetrahydronaphthalen-1-yl-phenethyl ureas: synthesis and dual antibacterial-anticancer activities

Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases

Open MoA: revealing the mechanism of action (MoA) based on network topology and hierarchy

Characterization of an <i>in vitro</i> steatosis model simulating activated <i>de novo</i> lipogenesis in MAFLD patients

Novel styryl-thiazole hybrids as potential anti-Alzheimer's agents

Systematic transcriptional analysis of human cell lines for gene expression landscape and tumor representation

Oxidative, Genotoxic and Cytotoxic Damage Potential of Novel Borenium and Borinium Compounds

The acute effect of different NAD plus precursors included in the combined metabolic activators

Longitudinal metabolomics analysis reveals the acute effect of cysteine and NAC included in the combined metabolic activators

Drug repositioning targeting glutaminase reveals drug candidates for the treatment of Alzheimer's disease patients

Revisiting the role of serine metabolism in hepatic lipogenesis

Costunolide and Parthenolide Ameliorate MPP plus Induced Apoptosis in the Cellular Parkinson's Disease Model

Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase

Lipoic Acid Conjugated Boron Hybrids Enhance Wound Healing and Antimicrobial Processes

Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: a randomised, double-blinded, placebo-controlled phase-II trial

In Vitro Transcriptome Analysis of Cobalt Boride Nanoparticles on Human Pulmonary Alveolar Cells

Toxicity of Glycyl-l-Prolyl-l-Glutamate Pseudotripeptides: Cytotoxic, Oxidative, Genotoxic, and Embryotoxic Perspectives

<i>In Vitro</i> and <i>In Vivo</i> Neuroprotective Effects of Sarcosine

Discovery of therapeutic agents targeting <i>PKLR </i>for <i>NAFLD </i>using drug repositioning

Assessment of the neuroprotective potential of d-cycloserine and l-serine in aluminum chloride-induced experimental models of Alzheimer's disease: <i>In vivo</i> and <i>in vitro</i> studies

Boron Compounds Exhibit Protective Effects against Aluminum-Induced Neurotoxicity and Genotoxicity: In Vitro and In Vivo Study

Boron Nitride Nanoparticles Loaded with a Boron-Based Hybrid as a Promising Drug Carrier System for Alzheimer's Disease Treatment

Ameliorative Effects by Hexagonal Boron Nitride Nanoparticles against Beta Amyloid Induced Neurotoxicity

Therapeutic Potential of Ferulic Acid in Alzheimer's Disease

Prediction of drug candidates for clear cell renal cell carcinoma using a systems biology-based drug repositioning approach

Molecular Genetics and Cytotoxic Responses to Titanium Diboride and Zinc Borate Nanoparticles on Cultured Human Primary Alveolar Epithelial Cells

A Gene Co-Expression Network-Based Drug Repositioning Approach Identifies Candidates for Treatment of Hepatocellular Carcinoma

Synthesis and in Vitro Toxicity Assessment of Different Nano-Calcium Phosphate Nanoparticles

Multiomics Analysis Reveals the Impact of Microbiota on Host Metabolism in Hepatic Steatosis

Systems Biology Approaches to Decipher the Underlying Molecular Mechanisms of Glioblastoma Multiforme

A network-based approach reveals the dysregulated transcriptional regulation in non-alcoholic liver disease

Revealing the Molecular Mechanisms of Alzheimer's Disease Based on Network Analysis

Multi-omics approaches for revealing the complexity of cardiovascular disease

In vitro transcriptome response to propolis in differentiated SH-SY5Y neurons

Combined Metabolic Activators Decrease Liver Steatosis by Activating Mitochondrial Metabolism in Hamsters Fed with a High-Fat Diet

Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer's and Parkinson's Diseases

Safety and Efficacy Assessments to Take Antioxidants in Glioblastoma Therapy: From In Vitro Experiences to Animal and Clinical Studies

The Assessment of Selected miRNA Profile in Familial Mediterranean Fever

Boron-based hybrids as novel scaffolds for the development of drugs with neuroprotective properties

Promising potential of boron compounds against Glioblastoma: In Vitro antioxidant, anti-inflammatory and anticancer studies

Stratification of patients with clear cell renal cell carcinoma to facilitate drug repositioning

iNetModels 2.0: an interactive visualization and database of multi-omics data

Anticancer effects of novel NSAIDs derivatives on cultured human glioblastoma cells

Combined Metabolic Activators Accelerates Recovery in Mild-to-Moderate COVID-19

Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction

Addressing the heterogeneity in liver diseases using biological networks

Informing Pharmacokinetic Models With Physiological Data: Oral Population Modeling of L-Serine in Humans

Potential Anticancer Effect of Carvacrol Codrugs on Human Glioblastoma Cells

Revealing the Metabolic Alterations during Biofilm Development of <i>Burkholderia cenocepacia</i> Based on Genome-Scale Metabolic Modeling

Targeted Gene Candidates for Treatment and Early Diagnosis of Age-Related Macular Degeneration

Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey

Discovery of Functional Alternatively Spliced <i>PKM</i> Transcripts in Human Cancers

Glycyl-L-Prolyl-L-Glutamate Pseudotripeptides for Treatment of Alzheimer's Disease

Safety Assessments of Nickel Boride Nanoparticles on the Human Pulmonary Alveolar Cells by Using Cell Viability and Gene Expression Analyses

In vitro neuroprotective effects of farnesene sesquiterpene on alzheimer's disease model of differentiated neuroblastoma cell line